13 lines
679 B
Plaintext
13 lines
679 B
Plaintext
A standalone program for mapping and aligning cDNA sequences to a
|
|
genome. The program maps and aligns a single sequence with minimal
|
|
startup time and memory requirements, and provides fast batch
|
|
processing of large sequence sets. The program generates accurate
|
|
gene structures, even in the presence of substantial polymorphisms
|
|
and sequence errors, without using probabilistic splice site models.
|
|
Methodology underlying the program includes a minimal sampling
|
|
strategy for genomic mapping, oligomer chaining for approximate
|
|
alignment, sandwich DP for splice site detection, and microexon
|
|
identification with statistical significance testing.
|
|
|
|
WWW: http://www.gene.com/share/gmap
|