2000-07-09 23:17:40 -04:00
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CLUSTAL W Multiple Sequence Alignment Program
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ClustalW was written by Des Higgins (now at University College, Cork,
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Ireland) (des@chah.ucc.ie), Julie Thompson (julie@IGBMC.u-strasbg.fr),
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Toby Gibson, (Gibson@EMBL-Heidelberg.DE), and Franc'ois Jeanmougin
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(pingouin@igbmc.u-strasbg.fr). It is a complete rewrite and upgrade of
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the Clustal and ClustalV packages. which were developed by Des
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Higgins. New features include the ability to detect read different
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input formats (NBRF/PIR, Fasta, EMBL/Swissprot); align old alignments;
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produce phylogenetic trees after alignment (Neighbor Joining trees
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with a bootstrap option); write different alignment formats (Clustal,
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NBRF/PIR, GCG, PHYLIP); full command line interface. It is described
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in the following papers:
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Thompson, J.D., D. G. Higgins and T. J. Gibson. 1994. CLUSTAL W:
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improving the sensitivity of progressive multiple sequence alignment
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through sequence weighting, positions-specific gap penalties and
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weight matrix choice. Nucleic Acids Research 22: 4673-4680.
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Higgins, D. G., J. D. Thompson, and T. J. Gibson. 1996. Using
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CLUSTAL for multiple sequence alignments. Methods in Enzymology 266:
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383-402.
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2000-10-02 21:10:19 -04:00
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WWW: http://www-igbmc.u-strasbg.fr/BioInfo/ClustalX/Top.html
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