diff --git a/gnu/local.mk b/gnu/local.mk
index 229d869c8f..571df533fc 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -1043,7 +1043,6 @@ dist_patch_DATA =						\
   %D%/packages/patches/psm-ldflags.patch			\
   %D%/packages/patches/psm-repro.patch				\
   %D%/packages/patches/pulseaudio-fix-mult-test.patch		\
-  %D%/packages/patches/pulseaudio-glibc-2.27.patch		\
   %D%/packages/patches/pulseaudio-longer-test-timeout.patch	\
   %D%/packages/patches/pybugz-encode-error.patch		\
   %D%/packages/patches/pybugz-stty.patch			\
diff --git a/gnu/packages/patches/pulseaudio-glibc-2.27.patch b/gnu/packages/patches/pulseaudio-glibc-2.27.patch
deleted file mode 100644
index 79d86abeee..0000000000
--- a/gnu/packages/patches/pulseaudio-glibc-2.27.patch
+++ /dev/null
@@ -1,67 +0,0 @@
-Copied from:
-https://cgit.freedesktop.org/pulseaudio/pulseaudio/commit/?id=dfb0460fb4743aec047cdf755a660a9ac2d0f3fb
-
-
-From dfb0460fb4743aec047cdf755a660a9ac2d0f3fb Mon Sep 17 00:00:00 2001
-From: Tanu Kaskinen <tanuk@iki.fi>
-Date: Wed, 24 Jan 2018 03:51:49 +0200
-Subject: [PATCH] memfd-wrappers: only define memfd_create() if not already
- defined
-
-glibc 2.27 is to be released soon, and it will provide memfd_create().
-If glibc provides the function, we must not define it ourselves,
-otherwise building fails due to conflict between the two implementations
-of the same function.
-
-BugLink: https://bugs.freedesktop.org/show_bug.cgi?id=104733
----
- configure.ac                   | 3 +++
- src/pulsecore/memfd-wrappers.h | 7 ++++---
- 2 files changed, 7 insertions(+), 3 deletions(-)
-
-diff --git a/configure.ac b/configure.ac
-index 0084c86e..0eb44b08 100644
---- a/configure.ac
-+++ b/configure.ac
-@@ -610,6 +610,9 @@ AS_IF([test "x$enable_memfd" = "xyes" && test "x$HAVE_MEMFD" = "x0"],
-     [AC_MSG_ERROR([*** Your Linux kernel does not support memfd shared memory.
-                   *** Use linux v3.17 or higher for such a feature.])])
- 
-+AS_IF([test "x$HAVE_MEMFD" = "x1"],
-+    AC_CHECK_FUNCS([memfd_create]))
-+
- AC_SUBST(HAVE_MEMFD)
- AM_CONDITIONAL([HAVE_MEMFD], [test "x$HAVE_MEMFD" = x1])
- AS_IF([test "x$HAVE_MEMFD" = "x1"], AC_DEFINE([HAVE_MEMFD], 1, [Have memfd shared memory.]))
-diff --git a/src/pulsecore/memfd-wrappers.h b/src/pulsecore/memfd-wrappers.h
-index 3bed9b2b..c7aadfd3 100644
---- a/src/pulsecore/memfd-wrappers.h
-+++ b/src/pulsecore/memfd-wrappers.h
-@@ -20,13 +20,14 @@
-   License along with PulseAudio; if not, see <http://www.gnu.org/licenses/>.
- ***/
- 
--#ifdef HAVE_MEMFD
-+#if defined(HAVE_MEMFD) && !defined(HAVE_MEMFD_CREATE)
- 
- #include <sys/syscall.h>
- #include <fcntl.h>
- 
- /*
-- * No glibc wrappers exist for memfd_create(2), so provide our own.
-+ * Before glibc version 2.27 there was no wrapper for memfd_create(2),
-+ * so we have to provide our own.
-  *
-  * Also define memfd fcntl sealing macros. While they are already
-  * defined in the kernel header file <linux/fcntl.h>, that file as
-@@ -63,6 +64,6 @@ static inline int memfd_create(const char *name, unsigned int flags) {
- #define F_SEAL_WRITE    0x0008  /* prevent writes */
- #endif
- 
--#endif /* HAVE_MEMFD */
-+#endif /* HAVE_MEMFD && !HAVE_MEMFD_CREATE */
- 
- #endif
--- 
-2.16.2
-
diff --git a/gnu/packages/pulseaudio.scm b/gnu/packages/pulseaudio.scm
index bac92eafa9..45bc1ee54a 100644
--- a/gnu/packages/pulseaudio.scm
+++ b/gnu/packages/pulseaudio.scm
@@ -122,7 +122,7 @@ rates.")
 (define-public pulseaudio
   (package
     (name "pulseaudio")
-    (version "11.1")
+    (version "12.0")
     (source (origin
              (method url-fetch)
              (uri (string-append
@@ -130,7 +130,7 @@ rates.")
                    name "-" version ".tar.xz"))
              (sha256
               (base32
-               "17ndr6kc7hpv4ih4gygwlcpviqifbkvnk4fbwf4n25kpb991qlpj"))
+               "0i248rmwwlfx1r22aiy1wf5lmhixlznyasgqdb5w04gxr6yjshkf"))
              (modules '((guix build utils)))
              (snippet
               ;; Disable console-kit support by default since it's deprecated
@@ -141,7 +141,6 @@ rates.")
                     (string-append "#" all "\n")))
                  #t))
              (patches (search-patches
-                       "pulseaudio-glibc-2.27.patch"
                        "pulseaudio-fix-mult-test.patch"
                        "pulseaudio-longer-test-timeout.patch"))))
     (build-system gnu-build-system)
@@ -153,13 +152,6 @@ rates.")
                                               (assoc-ref %outputs "out")
                                               "/lib/udev/rules.d"))
        #:phases (modify-phases %standard-phases
-                 (replace 'bootstrap
-                   ;; TODO: Remove this custom bootstrap phase when
-                   ;; pulseaudio-glibc-2.27.patch is removed.
-                   (lambda _
-                     (patch-shebang "git-version-gen")
-                     (setenv "NOCONFIGURE" "1")
-                     (invoke "bash" "bootstrap.sh")))
                  (add-before 'check 'pre-check
                    (lambda _
                      ;; 'tests/lock-autospawn-test.c' wants to create a file
@@ -188,11 +180,7 @@ rates.")
        ("check" ,check)))
     (native-inputs
      `(("pkg-config" ,pkg-config)
-       ;; TODO: Remove "autoconf", "automake", and "libtool" from
-       ;; native-inputs when pulseaudio-glibc-2.27.patch is removed.
-       ("autoconf" ,autoconf)
-       ("automake" ,automake)
-       ("libtool" ,libtool)))
+       ("glib:bin" ,glib "bin")))
     (propagated-inputs
      ;; 'libpulse*.la' contain `-lgdbm' and `-lcap', so propagate them.
      `(("libcap" ,libcap)