diff --git a/doc/guix.texi b/doc/guix.texi
index d069b7f0e6..7bedb8660e 100644
--- a/doc/guix.texi
+++ b/doc/guix.texi
@@ -103,6 +103,7 @@ Copyright @copyright{} 2021 Josselin Poiret@*
 Copyright @copyright{} 2022 Remco van 't Veer@*
 Copyright @copyright{} 2022 Aleksandr Vityazev@*
 Copyright @copyright{} 2022 Philip M@sup{c}Grath@*
+Copyright @copyright{} 2022 Karl Hallsby@*
 
 Permission is granted to copy, distribute and/or modify this document
 under the terms of the GNU Free Documentation License, Version 1.3 or
@@ -36270,8 +36271,8 @@ The type of a bootloader configuration declaration.
 @cindex BIOS, bootloader
 The bootloader to use, as a @code{bootloader} object.  For now
 @code{grub-bootloader}, @code{grub-efi-bootloader},
-@code{grub-efi-netboot-bootloader}, @code{extlinux-bootloader} and
-@code{u-boot-bootloader} are supported.
+@code{grub-efi-netboot-bootloader}, @code{grub-efi-removable-bootloader},
+@code{extlinux-bootloader} and @code{u-boot-bootloader} are supported.
 
 @cindex ARM, bootloaders
 @cindex AArch64, bootloaders
@@ -36340,6 +36341,20 @@ NFS servers, you also need a properly configured DHCP server to make the booting
 over netboot possible.  For all this we can currently only recommend you to look
 for instructions about @acronym{PXE, Preboot eXecution Environment}.
 
+@vindex grub-efi-removable-bootloader
+@code{grub-efi-removable-bootloader} allows you to boot your system from
+removable media by writing the GRUB file to the UEFI-specification location of
+@file{/EFI/BOOT/BOOTX64.efi} of the boot directory, usually @file{/boot/efi}.
+This is also useful for some UEFI firmwares that ``forget'' their configuration
+from their non-volatile storage. Like @code{grub-efi-bootloader}, this can only
+be used if the @file{/sys/firmware/efi} directory is available.
+
+@quotation Note
+This @emph{will} overwrite the GRUB file from any other operating systems that
+also place their GRUB file in the UEFI-specification location; making them
+unbootable.
+@end quotation
+
 @item @code{targets}
 This is a list of strings denoting the targets onto which to install the
 bootloader.
@@ -36348,7 +36363,8 @@ The interpretation of targets depends on the bootloader in question.
 For @code{grub-bootloader}, for example, they should be device names
 understood by the bootloader @command{installer} command, such as
 @code{/dev/sda} or @code{(hd0)} (@pxref{Invoking grub-install,,, grub,
-GNU GRUB Manual}).  For @code{grub-efi-bootloader}, they should be mount
+GNU GRUB Manual}).  For @code{grub-efi-bootloader} and
+@code{grub-efi-removable-bootloader} they should be mount
 points of the EFI file system, usually @file{/boot/efi}.  For
 @code{grub-efi-netboot-bootloader}, @code{targets} should be the mount
 points corresponding to TFTP root directories served by your TFTP
diff --git a/gnu/bootloader/grub.scm b/gnu/bootloader/grub.scm
index 120cd55012..65d7171432 100644
--- a/gnu/bootloader/grub.scm
+++ b/gnu/bootloader/grub.scm
@@ -7,6 +7,7 @@
 ;;; Copyright © 2019, 2020 Miguel Ángel Arruga Vivas <rosen644835@gmail.com>
 ;;; Copyright © 2020 Maxim Cournoyer <maxim.cournoyer@gmail.com>
 ;;; Copyright © 2020 Stefan <stefan-guix@vodafonemail.de>
+;;; Copyright © 2022 Karl Hallsby <karl@hallsby.com>
 ;;;
 ;;; This file is part of GNU Guix.
 ;;;
@@ -50,10 +51,12 @@
             grub-theme-color-highlight
             grub-theme-gfxmode
 
+            install-grub-efi-removable
             install-grub-efi-netboot
 
             grub-bootloader
             grub-efi-bootloader
+            grub-efi-removable-bootloader
             grub-efi-netboot-bootloader
             grub-mkrescue-bootloader
             grub-minimal-bootloader
@@ -608,6 +611,31 @@ fi~%"))))
                         "--bootloader-id=Guix"
                         "--efi-directory" target-esp)))))
 
+(define install-grub-efi-removable
+  #~(lambda (bootloader efi-dir mount-point)
+      ;; NOTE: mount-point is /mnt in guix system init /etc/config.scm /mnt/point
+      ;; NOTE: efi-dir comes from target list of booloader configuration
+      ;; There is nothing useful to do when called in the context of a disk
+      ;; image generation.
+      (when efi-dir
+        ;; Install GRUB onto the EFI partition mounted at EFI-DIR, for the
+        ;; system whose root is mounted at MOUNT-POINT.
+        (let ((grub-install (string-append bootloader "/sbin/grub-install"))
+              (install-dir (string-append mount-point "/boot"))
+              ;; When installing Guix, it's common to mount EFI-DIR below
+              ;; MOUNT-POINT rather than /boot/efi on the live image.
+              (target-esp (if (file-exists? (string-append mount-point efi-dir))
+                              (string-append mount-point efi-dir)
+                              efi-dir)))
+          ;; Tell 'grub-install' that there might be a LUKS-encrypted /boot or
+          ;; root partition.
+          (setenv "GRUB_ENABLE_CRYPTODISK" "y")
+          (invoke/quiet grub-install "--boot-directory" install-dir
+                        "--removable"
+                        ;; "--no-nvram"
+                        "--bootloader-id=Guix"
+                        "--efi-directory" target-esp)))))
+
 (define (install-grub-efi-netboot subdir)
   "Define a grub-efi-netboot bootloader installer for installation in SUBDIR,
 which is usually efi/Guix or efi/boot."
@@ -734,6 +762,12 @@ considered for security aspects."
    (name 'grub-efi)
    (package grub-efi)))
 
+(define grub-efi-removable-bootloader
+  (bootloader
+   (inherit grub-efi-bootloader)
+   (name 'grub-efi-removable-bootloader)
+   (installer install-grub-efi-removable)))
+
 (define grub-efi-netboot-bootloader
   (bootloader
    (inherit grub-efi-bootloader)