You can enable this module by creating a symbolic link from ${PREFIX}/conf/php5.sample/apc.ini to ${PREFIX}/conf/php5/apc.ini. ln -fs ${PREFIX}/conf/php5.sample/apc.ini \ ${PREFIX}/conf/php5/apc.ini If you already have Apache running on your machine, you should not use "apachectl restart" - instead, you should fully stop and then restart the server. You'll also need to configure APC using various settings in php.ini. See ${PREFIX}/pecl-APC/INSTALL for details.