diff --git a/biology/vsearch/Makefile b/biology/vsearch/Makefile
index 99d003441aa3..341b921fbf76 100644
--- a/biology/vsearch/Makefile
+++ b/biology/vsearch/Makefile
@@ -1,6 +1,6 @@
 PORTNAME=		vsearch
 DISTVERSIONPREFIX=	v
-DISTVERSION=		2.21.1
+DISTVERSION=		2.21.2
 CATEGORIES=		biology
 
 MAINTAINER=	jwb@FreeBSD.org
diff --git a/biology/vsearch/distinfo b/biology/vsearch/distinfo
index 85343620dba7..302a7dc12ee4 100644
--- a/biology/vsearch/distinfo
+++ b/biology/vsearch/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1642976868
-SHA256 (torognes-vsearch-v2.21.1_GH0.tar.gz) = 0c5f4c981bc8ecbf23ee618d1b45667f81ae9845d64b9d6a310edbd196c84638
-SIZE (torognes-vsearch-v2.21.1_GH0.tar.gz) = 257434
+TIMESTAMP = 1663095644
+SHA256 (torognes-vsearch-v2.21.2_GH0.tar.gz) = 841361c5e2081945177f6a63e2a85674b8c2aa439ad2b81dfc44b2a6c0b4b484
+SIZE (torognes-vsearch-v2.21.2_GH0.tar.gz) = 257953