diff --git a/misc/snakemake/Makefile b/misc/snakemake/Makefile
index d470ebec565d..ccc1748613d5 100644
--- a/misc/snakemake/Makefile
+++ b/misc/snakemake/Makefile
@@ -1,5 +1,5 @@
 PORTNAME=	snakemake
-DISTVERSION=	6.11.1
+DISTVERSION=	6.12.1
 CATEGORIES=	misc python
 MASTER_SITES=	CHEESESHOP
 
diff --git a/misc/snakemake/distinfo b/misc/snakemake/distinfo
index dc34ad3616a2..5c43995e3c88 100644
--- a/misc/snakemake/distinfo
+++ b/misc/snakemake/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1637960820
-SHA256 (snakemake-6.11.1.tar.gz) = fd99230d5e426dde38b9bc085f3796506185bb79a9c439b5300e662b2d424463
-SIZE (snakemake-6.11.1.tar.gz) = 278039
+TIMESTAMP = 1638513491
+SHA256 (snakemake-6.12.1.tar.gz) = 6bc45e98c0cd90d8e696ff09ad87cddf815baf50bd75964ea01639c9699ca50d
+SIZE (snakemake-6.12.1.tar.gz) = 278675