diff --git a/biology/plink/Makefile b/biology/plink/Makefile
index 3b32b57983ce..8467defbc94b 100644
--- a/biology/plink/Makefile
+++ b/biology/plink/Makefile
@@ -12,7 +12,7 @@ COMMENT=	Whole genome association analysis toolset
 LICENSE=	GPLv3
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
-NOT_FOR_ARCHS=		aarch64 mips64 powerpc64 sparc64
+NOT_FOR_ARCHS=		aarch64 mips64 powerpc64 powerpc64le sparc64
 NOT_FOR_ARCHS_REASON=	64bit code requires SSE2 instructions
 
 USES=		gmake fortran