diff --git a/biology/Makefile b/biology/Makefile
index 0622b83369d4..b544cbf16e59 100644
--- a/biology/Makefile
+++ b/biology/Makefile
@@ -41,6 +41,7 @@
     SUBDIR += emboss
     SUBDIR += erminej
     SUBDIR += exonerate
+    SUBDIR += fasda
     SUBDIR += fasta
     SUBDIR += fasta3
     SUBDIR += fastahack
diff --git a/biology/fasda/Makefile b/biology/fasda/Makefile
new file mode 100644
index 000000000000..eeca4cc01c9f
--- /dev/null
+++ b/biology/fasda/Makefile
@@ -0,0 +1,25 @@
+PORTNAME=	fasda
+DISTVERSION=	0.1.2
+CATEGORIES=	biology
+
+MAINTAINER=	jwb@FreeBSD.org
+COMMENT=	Fast and simple differential analysis
+WWW=		https://github.com/auerlab/fasda
+
+LICENSE=	BSD2CLAUSE
+LICENSE_FILE=	${WRKSRC}/LICENSE
+
+LIB_DEPENDS=	libxtend.so:devel/libxtend libbiolibc.so:biology/biolibc
+
+USES=		localbase
+USE_GITHUB=	yes
+
+GH_ACCOUNT=	auerlab
+
+MAKE_ENV=	VERSION=${PORTVERSION}
+INSTALL_TARGET=	install-strip
+
+pre-build:
+	cd ${WRKSRC} && make depend LOCALBASE=${LOCALBASE}
+
+.include <bsd.port.mk>
diff --git a/biology/fasda/distinfo b/biology/fasda/distinfo
new file mode 100644
index 000000000000..c0cdeca0ea7c
--- /dev/null
+++ b/biology/fasda/distinfo
@@ -0,0 +1,3 @@
+TIMESTAMP = 1670865129
+SHA256 (auerlab-fasda-0.1.2_GH0.tar.gz) = ea6003795b462286d4b7ea11924f424cdea418a345ceeccd1a04d679edf2374e
+SIZE (auerlab-fasda-0.1.2_GH0.tar.gz) = 57295
diff --git a/biology/fasda/pkg-descr b/biology/fasda/pkg-descr
new file mode 100644
index 000000000000..7a5c92fa13d8
--- /dev/null
+++ b/biology/fasda/pkg-descr
@@ -0,0 +1,5 @@
+FASDA aims to provide a fast and simple differential analysis tool
+that just works and does not require any knowledge beyond basic Unix
+command-line skills. The code is written entirely in C to maximize
+efficiency and portability, and to provide a simple command-line user
+interface.
diff --git a/biology/fasda/pkg-plist b/biology/fasda/pkg-plist
new file mode 100644
index 000000000000..939aed76df22
--- /dev/null
+++ b/biology/fasda/pkg-plist
@@ -0,0 +1,10 @@
+bin/fasda
+libexec/fasda/abundance
+libexec/fasda/fold-change
+libexec/fasda/normalize
+libexec/fasda/pval-sim
+man/man1/fasda-abundance.1.gz
+man/man1/fasda-fold-change.1.gz
+man/man1/fasda-normalize.1.gz
+man/man1/fasda-pval-sim.1.gz
+man/man1/fasda.1.gz