diff --git a/science/R-cran-Epi/Makefile b/science/R-cran-Epi/Makefile
index fcaa956aa5a0..860f65db29c4 100644
--- a/science/R-cran-Epi/Makefile
+++ b/science/R-cran-Epi/Makefile
@@ -1,7 +1,7 @@
 # Created by: TAKATSU Tomonari <tota@FreeBSD.org>
 
 PORTNAME=	Epi
-PORTVERSION=	2.44
+PORTVERSION=	2.46
 CATEGORIES=	science
 DISTNAME=	${PORTNAME}_${PORTVERSION}
 
@@ -12,7 +12,6 @@ LICENSE=	GPLv2
 
 CRAN_DEPENDS=	R-cran-cmprsk>0:science/R-cran-cmprsk \
 		R-cran-etm>0:science/R-cran-etm \
-		R-cran-purrr>0:devel/R-cran-purrr \
 		R-cran-plyr>0:devel/R-cran-plyr \
 		R-cran-dplyr>0:math/R-cran-dplyr \
 		R-cran-numDeriv>0:math/R-cran-numDeriv \
diff --git a/science/R-cran-Epi/distinfo b/science/R-cran-Epi/distinfo
index ec48d8649fdd..9ceeafaa3d54 100644
--- a/science/R-cran-Epi/distinfo
+++ b/science/R-cran-Epi/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1614578502
-SHA256 (Epi_2.44.tar.gz) = 20f4fe7748fe03ce9583c443db7b87b9434f4238c66df23f6feee5785cc89df1
-SIZE (Epi_2.44.tar.gz) = 3280540
+TIMESTAMP = 1650165415
+SHA256 (Epi_2.46.tar.gz) = e07f8714b9f000a54dc6ffe840bbba3eb420f91d9ab079d23c8d13e533907168
+SIZE (Epi_2.46.tar.gz) = 3514912