diff --git a/biology/mothur/files/patch-source_endiannessmacros.h b/biology/mothur/files/patch-source_endiannessmacros.h
new file mode 100644
index 000000000000..923cfbd9e621
--- /dev/null
+++ b/biology/mothur/files/patch-source_endiannessmacros.h
@@ -0,0 +1,19 @@
+--- source/endiannessmacros.h.orig	2020-10-19 10:22:23 UTC
++++ source/endiannessmacros.h
+@@ -53,16 +53,6 @@
+ #  define SP_BIG_ENDIAN
+ #endif
+ 
+-/*
+- * PowerPC
+- */
+-#if defined(__ppc__) || defined(__ppc)
+-#  if defined(SP_LITTLE_ENDIAN)
+-#    undef SP_LITTLE_ENDIAN
+-#  endif
+-#  define SP_BIG_ENDIAN
+-#endif
+-
+ /* Some catch-alls */
+ #if defined(__LITTLE_ENDIAN__) || defined(__LITTLEENDIAN__)
+ #    define SP_LITTLE_ENDIAN